Journal of IMAB (Dec 2011)

COGNITIVE DYSFUNCTIONS IN DIABETIC POLYNEUROPATHY

  • Mirena Valkova,
  • Boyko Stamenov,
  • Dora Peychinska

DOI
https://doi.org/10.5272/jimab.2011171.183
Journal volume & issue
Vol. 17, no. 1
pp. 183 – 188

Abstract

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Introduction: The objective of our study was to examine cognitive status, short – term memory, delayed recall and the retention of visual information in diabetics with polyneuropathy and to establish the impacts of some risk factors on cognitive performance.Contingent and methods: We assessed 47 diabetic patients with polyneuropathy, using the Mini Mental State Examination, 10 words test, the Benton visual retention test and the Hamilton scale.Results: Global cognitive dysfunction, decline in verbal memory and visual retention and tendency for depressive mood were observed. We found statistically significant interaction of ageing, sex, severity of pain, duration and late onset of diabetes mellitus (DM) on cognitive functioning. Therapy association on cognition was not found.Conclusions: Our study confirms the hypothesis of global cognitive dysfunction, associated with diabetic polyneuropathy. The interactions of sex and pain severity require further study. We arise a hypothesis of asymmetrical brain injury in diabetics.

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