State of Left Ventricular Systolic and Diastolic Function in Patients with Postinfarction Cardiosclerosis and Obesity

Abstract

Cardiovascular diseases are one of the major causes of mortality worldwide, the main contribution to its structure belongs to ischemic heart disease. One of the major factors for the progression of ischemic heart disease is obesity. The objective of the work — to carry out an analysis of the state of left ventricular systolic and diastolic function in patients with postinfarction cardiosclerosis and obesity. Materials and Methods. The study retrospectively included 76 patients with ischemic heart disease, who had myocardial infarction, with concomitant obesity. Comparison group consisted of 80 patients with ischemic heart disease, who had myocardial infarction, without obesity. All patients underwent general clinical and instrumental examination. Statistical analysis of the data was performed using the statistical software package Statistica 8.0, Microsoft Office Excel 2003. Results. It is found that the degree of reduction in left ventricular contractility is an important indicator of myocardial compensatory reserves exhaustion and has a significant impact on the severity of clinical manifestations in patients with postinfarction cardiosclerosis and obesity. Conclusions. Comorbidity of obesity and postinfarction remodeling potentiate the increase of the heart size, dilatation of the heart cavities on the background of inotropic myocardial function reduction. In most patients with postinfarction cardiosclerosis and obesity, left ventricular diastolic dysfunction manifested by a type of relaxation disturbance.

Keywords

• postinfarction cardiosclerosis
• obesity
• systolic function
• diastolic function