Local Recurrence of Invasive Secretory Breast Carcinoma in a Gravid Patient Post-Mastectomy

Sneha S Shukla, MD; Asha A Bhatt, MD; James W Jakub, MD; Malvika H Solanki, MBBS, MPH, PhD; Aparna S Kaur, MD; Minetta C Liu, MD; Kimberly S Corbin, MD; Jessica A Axmacher, MD

Radiology Case Reports (Jun 2022)

Local Recurrence of Invasive Secretory Breast Carcinoma in a Gravid Patient Post-Mastectomy

Sneha S Shukla, MD,
Asha A Bhatt, MD,
James W Jakub, MD,
Malvika H Solanki, MBBS, MPH, PhD,
Aparna S Kaur, MD,
Minetta C Liu, MD,
Kimberly S Corbin, MD,
Jessica A Axmacher, MD

Affiliations

Sneha S Shukla, MD: Department of Radiology, Mayo Clinic, 200 1st Street SW, Rochester, MN, 55905, USA; Corresponding author.
Asha A Bhatt, MD: Department of Radiology, Mayo Clinic, 200 1st Street SW, Rochester, MN, 55905, USA
James W Jakub, MD: Department of General Surgery, Mayo Clinic, 200 1st Street SW, Rochester, MN, 559050, USA
Malvika H Solanki, MBBS, MPH, PhD: Department of Laboratory Science and Pathology, Mayo Clinic, 200 1st Street SW, Rochester, MN, 55905, USA
Aparna S Kaur, MD: Department of General Internal Medicine, Mayo Clinic, 200 1st Street SW, Rochester, MN, 55905, USA
Minetta C Liu, MD: Department of Medical Oncology, Mayo Clinic, 200 1st Street SW, Rochester, MN, 55905, USA
Kimberly S Corbin, MD: Department of Radiation Oncology, Mayo Clinic, 200 1st Street SW, Rochester, MN, 55905, USA
Jessica A Axmacher, MD: Department of Radiology, Mayo Clinic, 200 1st Street SW, Rochester, MN, 55905, USA

Journal volume & issue: Vol. 17, no. 6
pp. 1901 – 1904

Abstract

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This is a case of locally recurrent invasive secretory carcinoma of the breast during pregnancy, detected as a palpable mass in the reconstructed right breast of a 32-year-old female at 24 weeks gestation. The patient was initially diagnosed with secretory carcinoma 8 years prior, for which she underwent nipple sparing mastectomy followed by adjuvant chemotherapy and endocrine therapy. Due to pregnancy, the recurrence was treated initially with conservative excision alone, followed by definitive management postpartum which included wide local excision, sentinel lymph node biopsy and adjuvant chest wall radiation. Secretory carcinoma of the breast is a rare cancer with a predilection for young age and indolent course. This case report describes an unusual case of recurrent secretory carcinoma, of interest due to both its diagnosis during pregnancy, and its recurrence after nipple sparing mastectomy.

Published in Radiology Case Reports

ISSN: 1930-0433 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Medicine: Medicine (General): Medical physics. Medical radiology. Nuclear medicine
Website: https://www.sciencedirect.com/journal/radiology-case-reports

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