Association of <i>Euterpe oleracea</i>, <i>Bixa orellana</i>, <i>Myciaria dubia</i>, and <i>Astrocaryum aculeatum</i> (the Terasen^® Nutraceutical) Increases the Lifespan of <i>Caenorhabditis elegans</i>

Abstract

Aging is a complex process associated with tissue degeneration and an increased risk of age-related diseases. This study aimed to evaluate the impact of Terasen®, a nutraceutical containing standardized extracts of Euterpe oleracea, Myrciaria dubia, and purified oil of Bixa orellana and Astrocaryum aculeatum on the lifespan of Caenorhabditis elegans. The findings demonstrated that Terasen® exhibited significant radical scavenging in vitro, decreased the feeding behavior of C. elegans without affecting the animals’ final size, increased the eggs laid in a concentration-dependent fashion, although the total progeny was reduced compared to the control, and increased the median and maximum lifespan. These findings suggest that Terasen® may improve the lifespan in C. elegans, warranting further investigation.

Keywords

• longevity
• healthspan
• lifespan
• nutraceuticals
• <i>C. elegans</i>