Drug Design, Development and Therapy (Jun 2023)
Endoplasmic Reticulum Stress-Induced Autophagy Determines the Susceptibility of Melanoma Cells to Dabrafenib [Retraction]
Abstract
Ji C, Zhang Z, Chen L, et al. Drug Des Devel Ther. 2016;10:2491–2498. The Editor and Publisher of Drug Design, Development and Therapy are retracting the published article. Concerns were raised regarding the western blot analysis, and it was found that some western blot bands appeared to have been duplicated with those from Zhang Y, Chen C, Jiang Y, et al. PPARγ coactivator-1α (PGC-1α) protects neuroblastoma cells against amyloid-beta (Aβ) induced cell death and neuroinflammation via NF-κB pathway. BMC Neurosci. 2017;18:69. https://doi.org/10.1186/s12868-017-0387-7. Specifically, The western blot image for Figure 3B, A375, IRE1α, appears to have been duplicated with the image for Figure 4a, Nucleus, NF-κB p65 from Zhang et al (2017). The western blot image for Figure 3B, A375, p62, appears to have been duplicated with the image for Figure 4a, Cytoplasm, NF-κB p65 from Zhang et al (2017). The western blot image for Figure 3B, A375, β-actin, appears to have been duplicated with the image for Figure 4a, Cytoplasm, β-actin from Zhang et al (2017). The authors did not respond to our queries and did not provide any original data for their study. As the findings could not be adequately verified the Editor and Publisher made the decision to retract the article and the authors were notified of this. We have been informed in our decision-making by our editorial policies and the COPE guidelines. The retracted article will remain online to maintain the scholarly record, but it will be digitally watermarked on each page as “Retracted”.
