Nature Communications (Feb 2021)

Network models of primary melanoma microenvironments identify key melanoma regulators underlying prognosis

  • Won-Min Song,
  • Praveen Agrawal,
  • Richard Von Itter,
  • Barbara Fontanals-Cirera,
  • Minghui Wang,
  • Xianxiao Zhou,
  • Lara K. Mahal,
  • Eva Hernando,
  • Bin Zhang

DOI
https://doi.org/10.1038/s41467-021-21457-0
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 14

Abstract

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While the molecular profiling of melanoma progression has been extensively characterised by large-scale studies, there is still need for the comprehensive integration of such datasets. Here the authors construct predictive gene network models for prognostic and therapeutic purposes.