Infection and Drug Resistance (Aug 2022)
Incidence of Death and Its Predictors of COVID-19 in Amhara Region, Ethiopia: A Retrospective Follow Up Study
Abstract
Anteneh Mengist Dessie,1 Zelalem Animut,2 Almaw Genet,3 Chalachew Yenew1 1Department of Public Health, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia; 2Department of Public Health, Fahoba Health and Business College, Debre Markos, Ethiopia; 3Department of Public Health, College of Health Sciences, Bahir Dar University, Bahir Dar, EthiopiaCorrespondence: Chalachew Yenew, Tel +251945563008, Email [email protected]: Risk factors associated with COVID-19 incidence of death would aid to notify the most favorable management strategies, hang about undecided, Moreover, studies regarding this issue are limited in Ethiopia and no region-wise study is conducted. Hence, the study investigated the COVID-19 incidence of death and its predictors in the Amhara regional state, Ethiopia.Methods: A facility-based retrospective survey was conducted at all Amhara regional state COVID-19 treatment centers from 13 March 2020, through 13 January 2022. Epidata version 3.1 and STATA version 14 were used for data entry and analysis, respectively. Linearized survey analysis in a stratified Cox regression model was fitted to identify independent risk factors. P-value with 95% CI for hazard ratio was used for testing the significance at alpha 0.05.Results: A total of 28,533 study participants were analyzed in this study. Of these, 2873 (11.2%) died and 25,660 (88.8%) were recovered from COVID-19. The death rate was 11.78 per 1000 person-days of observation with a median survival time of 32 days with IQR [12, 44]. Patients with co-morbidities (AHR = 1.54: 95% CI: 1.51– 1.55), patients with age < 5-year (AHR = 1.69: 95% CI: 1.78– 1.81) and patients with age 60+ years (AHR = 2.91: 95% CI: 1.79– 3.99), patients with asymptomatic diseases condition (AHR =1.15: 95% CI: 1.01– 1.19), and being male (AHR = 1.22: 95% CI: 1.18– 1.27) were independent significant risk factors of death from COVID-19.Conclusion: A relatively high incidence of death from COVID-19 was found in this study. Significant risk factors were identified as patients with age < 5 years, patients with age 60+ Years, being male, patients having at least one comorbid condition, and patients with asymptomatic disease conditions. These factors should be taken into consideration for a strategy of quarantining and treating COVID-19 patients.Keywords: incidence of death, predictors, COVID-19, cox regression model
