Intensified Hyposensitization Is an Effective Treatment of Postorgasmic Illness Syndrome (POIS)

Joanna Wrotynska-Barczynska, MD; Edyta Swat, MD; Anna Berger, MSc; Leszek Pawelczyk, MD, PhD; Piotr Jedrzejczak, MD, PhD

Sexual Medicine (Apr 2022)

Intensified Hyposensitization Is an Effective Treatment of Postorgasmic Illness Syndrome (POIS)

Joanna Wrotynska-Barczynska, MD,
Edyta Swat, MD,
Anna Berger, MSc,
Leszek Pawelczyk, MD, PhD,
Piotr Jedrzejczak, MD, PhD

Affiliations

Joanna Wrotynska-Barczynska, MD: Department of Infertility and Reproductive Endocrinology, Poznan University of Medical Sciences, Poznan, Poland; Corresponding Author: Joanna Wrotynska-Barczynska, MD, Department of Infertility and Reproductive Endocrinology, Poznan University of Medical Sciences, Poznan, Poland, Fredry 10, 61-701 Poznań, Phone: +48 (Poland) 61 (Poznan) 854 62 28; fax: 852 04 55
Edyta Swat, MD: Department of Pulmonology and Allergology, Poznan University of Medical Sciences, Poznan, Poland
Anna Berger, MSc: Department of Infertility and Reproductive Endocrinology, Poznan University of Medical Sciences, Poznan, Poland
Leszek Pawelczyk, MD, PhD: Department of Infertility and Reproductive Endocrinology, Poznan University of Medical Sciences, Poznan, Poland
Piotr Jedrzejczak, MD, PhD: Department of Infertility and Reproductive Endocrinology, Poznan University of Medical Sciences, Poznan, Poland; Piotr Jedrzejczak, MD PhD, Department of Infertility and Reproductive Endocrinology, Poznan University of Medical Sciences, Poznan, Poland, Fredry 10, 61-701 Poznań, Phone: +48 (Poland) 61 (Poznan) 854 62 28; fax: 852 04 55

Journal volume & issue: Vol. 10, no. 2
p. 100474

Abstract

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ABSTRACT: Introduction: Postorgasmic illness syndrome (POIS) is an extremely rare urogenital disease which significantly and negatively impacts the functioning and sexual activity. Aims: A 34-year-old male presented with POIS symptoms and confirmed the allergic component of the POIS. Intensified immunotherapy with autologous semen was recommended. Methods: The treatment lasted 14 months and included 20 visits. Modified and intensified subcutaneous immunotherapy in both forearms significantly shortened the therapy and improved the outcome, with high-tolerance and no adverse effects or hyperactive responses. Main Outcome Measure: Improvement in POIS symptoms through the use of intensified immunotherapy with autologous semen. Results: The improvement was significant enough to allow for higher sexual activity, and gradual resumption of private and professional activity. Conclusion: Intensified immunotherapy with autologous semen seems an effective and safe option for treating patients with suspected immune-allergenic POIS. To the best of our knowledge, this has been the first such intensive and effective allergen-specific immunotherapy of POIS.Wrotynska-Barczynska J, Swat. Swat E, Berger A, et al. Intensified Hyposensitization Is an Effective Treatment of Postorgasmic Illness Syndrome (POIS). Sex Med 2022;10:100474.

Published in Sexual Medicine

ISSN: 2050-1161 (Online)
Publisher: Oxford University Press
Country of publisher: United Kingdom
LCC subjects: Medicine
Website: https://academic.oup.com/smoa

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Abstract

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