Free Radical Oxidation and its Part in Hypoxia Adaptation in Epistaxis

Abstract

Purpose: A comparative study of free radical oxidation in the blood of those suffering from single and recurrent epistaxis.Materials and Methods: In 98 patients malon dialdegid, superoxiddismutase and total peroxidase activity of blood red cells were examined.Results: Recurrent epistaxis is shown to be followed by a deteriorated content of red blood cells and haemoglobin, which may result in hypoxia. In this group, FRO takes part in hypoxia adaptation: increased superoxide scavenger activity protects red cells from oxidative damage. Physical exercise tests have proved a low reserve of the anti-oxidant system in the blood of recurrent epistaxis patients.Summary: The state of the patient, suffering from recurrent epistaxis depends on free radical oxidation system reserves.

Keywords

• free radical oxidation
• hypoxia
• epistaxis