International Medical Case Reports Journal (Nov 2023)
Primary Tracheobronchial Amyloidosis Presenting with an Upper Airway Obstruction
Abstract
Zekewos Demissie,1 Nahom Zemedkun,1 Abraham Demile,1 Berhanu Nega,2 Yonas Bekuretsion,3 Bisrat Getachew,4 Bethelhem Berhanu5 1Department of Internal Medicine, Lancet General Hospital, Addis Ababa, Ethiopia; 2Department of Surgery, Division of Cardiothoracic Surgery, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia; 3Department of Pathology, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia; 4Department of Otolaryngology, Head and Neck Surgery, St. Paul Millennium Medical College, Addis Ababa, Ethiopia; 5Department of Radiology, St. Paul Millennium Medical College, Addis Ababa, EthiopiaCorrespondence: Zekewos Demissie, Email [email protected]: This is a case of localized primary tracheobronchial amyloidosis in a patient who presented with upper airway obstruction. Tracheobronchial amyloidosis is a type of localized bronchopulmonary amyloidosis that is frequently overlooked. It involves the deposition of amyloid protein on the tracheal and bronchial tissue, leading to progressive tracheal stenosis and airway obstruction that can be seen on imaging as a tracheal mass. Because of its significant diagnostic difficulty and therapeutic conundrum, it ought to be considered in the differential diagnosis of upper airway symptoms with an unknown etiology.Keywords: tracheobronchial amyloidosis, tracheal mass, upper airway obstruction