Mixtures of Micro and Nanoplastics and Contaminants of Emerging Concern in Environment: What We Know about Their Toxicological Effects

Abstract

In real environments, pollutants do not occur in isolation. Instead, they can be found in complex mixtures with effects that are completely different from those of the individual components. In this review, articles from 2017 to May 2024 have been selected to provide an overview of the existing knowledge on complex mixtures between micropollutants and micro and nanoplastics in organisms in terrestrial and aquatic environments. It was found that the corresponding toxicological parameters to determine the interaction between the compounds were not calculated in most of the literature reviewed. Our analysis shows that, in aquatic environments, synergistic effects have been found more frequently than antagonistic effects. In terrestrial environments, the joint toxicological action of microplastics or nanoplastics with emerging contaminants has been less studied, but synergistic effects may also predominate. Future work should thoroughly investigate the nature of the interactions in order to properly assess the risk posed by this cocktail of compounds in ecosystems.

Keywords

• microplastics
• micropollutants
• combined toxicity