Российский кардиологический журнал (Feb 2010)

HIGH PREVALENCE OF METABOLIC SYNDROME IN SIBERIAN MEN WITH CORONARY ATHEROSCLEROSIS

  • M. I. Voevoda,
  • Yu. I. Ragino,
  • A. M. Chernyavsky,
  • S. Yu. Tsymbal,
  • E. V. Semaeva,
  • Ya. V. Polonskaya,
  • M. V. Ivanova

Journal volume & issue
Vol. 0, no. 1
pp. 65 – 69

Abstract

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In 42-70-year-old Siberian men with coronary atherosclerosis, verified by coronary angiography, the prevalence of metabolic syndrome (MS) was as high as 89%, which suggests an important role of MS in atherosclerosis development in the Siberian region. In pre-existing coronary atherosclerosis, biomarkers of inflammation and destruction (highly sensitive C-reactive protein, inflammatory cytokines, and destructive metalloproteinases) correlated with MS components, reflecting the pathophysiological role of inflammation in MS development.

Keywords