Jichu yixue yu linchuang (Mar 2023)

Advances in the study of the correlation between vitamin D-24-hydroxylase and thyroid carcinoma

  • CHEN Shijing, FU Jinglan, DENG Yuanyuan, ZHANG Ying, LIU Huixia

DOI
https://doi.org/10.16352/j.issn.1001-6325.2023.03.490
Journal volume & issue
Vol. 43, no. 3
pp. 490 – 494

Abstract

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Thyroid carcinoma(TC) is the most common malignant tumor of endocrine system. Patients with vitamin D deficiency have an increased risk of TC. Vitamin D-24-hydroxylase (CYP24A1) is main inactivating enzyme of active vitamin D which may inhibit the antiproliferative effect of vitamin D and promote the development of TC by inactivating 1,25-dihydroxyvitamin D3.

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