Clinical, Cosmetic and Investigational Dermatology (Nov 2021)
A Study on the Fabrication of an Effective Natural Substance Based on Schisandra chinensis Extracted Fermentation
Abstract
Chi Thanh Nguyen,1 Jong-Man Han,2 Van Huong Tran,3 Hun Jeong,4 Eun Sook Kim5 1Department of Materials Technology, Faculty of Applied Sciences, Ho Chi Minh City University of Technology and Education, Ho Chi Minh City, 700000, Viet Nam; 2Department of Physical Therapy, Daegu Health College, Daegu, 41453, Republic of Korea; 3School of Mechanical Engineering, Hanoi University of Science and Technology, Ha Noi, 100000, Viet Nam; 4Department of Nano Convergence Engineering, Polymer Materials Fusion Research Center, Jeonbuk National University, Jeonju, Jeonbuk, 54896, Republic of Korea; 5Department of Beauty-Therapy & Make Up, Seokyeong University, Seoul, 02713, Republic of KoreaCorrespondence: Hun Jeong; Eun Sook Kim Email [email protected]; [email protected]: In this study, a high-efficiency Schisandra chinensis extract (SCE) produced by the fermentation of effective microorganisms (EM) was used as an antioxidant material in preparing cosmetic products.Subjects and Methods: We conducted the study by extracting S. chinensis via EM fermentation to increase the efficiency. Tyrosinase inhibitory factor analysis, pH, and thermal stability were measured to verify the properties of the prepared products.Results: The efficacy and whitening effects of the prepared substances were verified using tyrosinase inhibitory factor analysis. As a result, it was found that both the SCE and SCE fermentation (SCEF) exhibited high, naturally originating, antioxidation ability. In addition, the pH and thermal stability of the substances were evaluated to optimize the cosmetic fabrication conditions. In this context, as the concentration of the added extract increased, the pH value decreased. The evaluation of safety and stability indicated that the substances contained effective chemical components having antioxidant activity, suppressing skin aging, and whitening effects in a weak acid range consistent with a pH of 6.25– 2.98. Furthermore, there were no safety problems with the use of the obtained products even after they had been stored for 60 days.Conclusion: The SCE substance is demonstrated as a possible material for cosmetic application.Keywords: Schisandra chinensis, effective microorganisms fermentation, antioxidation
