Applied Sciences (Sep 2021)

Metal Nanozymes: New Horizons in Cellular Homeostasis Regulation

  • Hanna Lewandowska,
  • Karolina Wójciuk,
  • Urszula Karczmarczyk

DOI
https://doi.org/10.3390/app11199019
Journal volume & issue
Vol. 11, no. 19
p. 9019

Abstract

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Nanomaterials with enzyme-like activity (nanozymes) have found applications in various fields of medicine, industry, and environmental protection. This review discusses the use of nanozymes in the regulation of cellular homeostasis. We also review the latest biomedical applications of nanozymes related to their use in cellular redox status modification and detection. We present how nanozymes enable biomedical advances and demonstrate basic design strategies to improve diagnostic and therapeutic efficacy in various diseases. Finally, we discuss the current challenges and future directions for developing nanozymes for applications in the regulation of the redox-dependent cellular processes and detection in the cellular redox state changes.

Keywords