Nature Communications (Sep 2019)

Human induced pluripotent stem cell-derived vocal fold mucosa mimics development and responses to smoke exposure

  • Vlasta Lungova,
  • Xia Chen,
  • Ziyue Wang,
  • Christina Kendziorski,
  • Susan L. Thibeault

DOI
https://doi.org/10.1038/s41467-019-12069-w
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 16

Abstract

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There is a lack of human models to study vocal fold epithelia making it difficult to provide therapies for vocal fold disease. Here, the authors generate a human-based model of vocal fold mucosa that mimics in utero development and shows inflammation on exposure to cigarette smoke abstract.