Nature Communications (Jan 2017)

Dietary fatty acid metabolism of brown adipose tissue in cold-acclimated men

  • Denis P. Blondin,
  • Hans C. Tingelstad,
  • Christophe Noll,
  • Frédérique Frisch,
  • Serge Phoenix,
  • Brigitte Guérin,
  • Éric E Turcotte,
  • Denis Richard,
  • François Haman,
  • André C. Carpentier

DOI
https://doi.org/10.1038/ncomms14146
Journal volume & issue
Vol. 8, no. 1
pp. 1 – 9

Abstract

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Brown adipose tissue (BAT) takes up and burns fatty acids for thermogenesis in mice. Here the authors use PET to show that, in humans, cold stimulation increases BAT dietary fatty acid uptake from plasma and oxidative metabolism, although, unlike mice, human BAT takes up less fatty acids than other metabolic tissues.