Clinical Epidemiology and Global Health (Jan 2025)

Association between sleep quality and ischemic heart disease: Insights from a case-control study

  • Ghada O. Wassif,
  • Shaimaa S. Yousef,
  • Hebat Allah M.S. Gabal

Journal volume & issue
Vol. 31
p. 101862

Abstract

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Background: Ischemic heart disease (IHD) significantly impacts global morbidity and mortality. Recent studies highlight a bidirectional relationship between cardiovascular health and sleep quality. This study investigates how IHD predicts poor sleep quality, emphasizing the need for integrated management of cardiovascular and sleep health. Methods: A case-control study was conducted at Ain Shams University Hospitals, Cairo, Egypt, involving 370 adults aged 40–75 years (185 cases, 185 controls). Data were collected using a standardized interview questionnaire covering socio-demographic data, IHD risk factors, and the Pittsburgh Sleep Quality Index (PSQI). Results: Significant risk factors for IHD included smoking, elevated blood pressure, obesity, and family history. Differences in sleep quality dimensions were observed between cases and controls. IHD, age, gender, and BMI were significant predictors of PSQI. Conclusion & Recommendation: The study underscores the significant association between IHD and poor sleep quality, highlighting the importance of considering sleep quality in managing IHD patients.

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