Experience with sertaconazole in pregnant women with vulvo-vaginal candidiasis

Abstract

Objective. To evaluate the clinical efficacy of sertaconazole in the treatment of acute vulvo-vaginal candidiasis (VVC) in pregnant women with caesarean section. Subject and methods. The study included 136 pregnant women. In the treatment, 1 candle of sertaconazole 300 mg once was used. Efficacy was evaluated after 7 and 28 days. Results. At 74.0% of pregnant women identified VVK. After treatment with sertaconazole, positive dynamics was observed in 91.9% of patients, in whom clinical manifestations of the disease disappeared by the third day. Culture testing revealed a normalization of the vaginal biotope at 97.1% of pregnant women. Our experience has shown the effectiveness of the drug, the absence of adverse events and good compliance due to the ease of use and rapid achievement of the therapeutic effect in pregnant women throughout pregnancy.

Keywords

• sertaconazole
• vulvo-vaginal candidiasis
• bacterial vaginosis
• prevention and treatment
• resistance