Diagnostics (Apr 2024)

Small Bowel Perforation Due to Renal Carcinoma Metastasis: A Comprehensive Case Study and Literature Review

  • Đorđe Todorovic,
  • Bojan Stojanovic,
  • Milutinovic Filip,
  • Đorđe Đorđevic,
  • Milos Stankovic,
  • Ivan Jovanovic,
  • Marko Spasic,
  • Bojan Milosevic,
  • Aleksandar Cvetkovic,
  • Dragce Radovanovic,
  • Marina Jovanovic,
  • Bojana S. Stojanovic,
  • Damnjan Pantic,
  • Danijela Cvetkovic,
  • Dalibor Jovanovic,
  • Vladan Markovic,
  • Milica Dimitrijevic Stojanovic

DOI
https://doi.org/10.3390/diagnostics14070761
Journal volume & issue
Vol. 14, no. 7
p. 761

Abstract

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This case report presents a unique instance of small bowel perforation caused by solitary metastasis from renal cell carcinoma (RCC), a rare and complex clinical scenario. The patient, a 59-year-old male with a history of RCC treated with nephrectomy four years prior, presented with acute abdomen symptoms. Emergency diagnostic procedures identified a significant lesion in the small intestine. Surgical intervention revealed a perforated jejunal segment due to metastatic RCC. Postoperatively, the patient developed complications, including pneumonia and multi-organ failure, leading to death 10 days after surgery. Histopathological analysis confirmed the metastatic nature of the lesion. This case underscores the unpredictable nature of RCC metastasis and highlights the need for vigilance in post-nephrectomy patients. The rarity of small bowel involvement by RCC metastasis, particularly presenting as perforation, makes this case a significant contribution to medical literature, emphasizing the challenges in the diagnosis and management of such atypical presentations.

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