Suppression of RUNX1/ETO oncogenic activity by a small molecule inhibitor of tetramerization

• Julia Schanda,
• Chun-Wei Lee,
• Katharina Wohlan,
• Uta Müller-Kuller,
• Hana Kunkel,
• Isabell Quagliano-Lo Coco,
• Stefan Stein,
• Alexander Metz,
• Joachim Koch,
• Jörn Lausen,
• Uwe Platzbecker,
• Hind Medyouf,
• Holger Gohlke,
• Michael Heuser,
• Matthias Eder,
• Manuel Grez,
• Michaela Scherr,
• Christian Wichmann

Affiliations

Julia Schanda

Institute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, Frankfurt, Germany

Chun-Wei Lee

Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Germany

Katharina Wohlan

Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Germany

Uta Müller-Kuller

Institute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, Frankfurt, Germany;German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, Germany

Hana Kunkel

Institute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, Frankfurt, Germany

Isabell Quagliano-Lo Coco

Institute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, Frankfurt, Germany;German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, Germany

Stefan Stein

Institute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, Frankfurt, Germany

Alexander Metz

Institute for Pharmaceutical and Medicinal Chemistry, Department of Mathematics and Natural Sciences, Heinrich Heine University Düsseldorf, Germany

Joachim Koch

Institute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, Frankfurt, Germany

Jörn Lausen

Institute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, Frankfurt, Germany

Uwe Platzbecker

Department of Hematology, Medical Clinic and Polyclinic I, University Hospital Carl Gustav Carus, Dresden, Germany

Hind Medyouf

Institute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, Frankfurt, Germany

Holger Gohlke

Institute for Pharmaceutical and Medicinal Chemistry, Department of Mathematics and Natural Sciences, Heinrich Heine University Düsseldorf, Germany

Michael Heuser

Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Germany

Matthias Eder

Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Germany

Manuel Grez

Institute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, Frankfurt, Germany

Michaela Scherr

Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Germany

Christian Wichmann

Institute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, Frankfurt, Germany;Department of Transfusion Medicine, Cell Therapeutics and Hemostaseology, Ludwig-Maximilian University Hospital, Munich, Germany