Modulation of dopamine tone induces frequency shifts in cortico-basal ganglia beta oscillations

L. Iskhakova; P. Rappel; M. Deffains; G. Fonar; O. Marmor; R. Paz; Z. Israel; R. Eitan; H. Bergman

doi:10.1038/s41467-021-27375-5

Nature Communications (Dec 2021)

Modulation of dopamine tone induces frequency shifts in cortico-basal ganglia beta oscillations

L. Iskhakova,
P. Rappel,
M. Deffains,
G. Fonar,
O. Marmor,
R. Paz,
Z. Israel,
R. Eitan,
H. Bergman

Affiliations

L. Iskhakova: Department of Medical Neurobiology, Institute of Medical Research Israel–Canada (IMRIC), The Hebrew University–Hadassah Medical School
P. Rappel: Department of Medical Neurobiology, Institute of Medical Research Israel–Canada (IMRIC), The Hebrew University–Hadassah Medical School
M. Deffains: University of Bordeaux, UMR 5293, IMN
G. Fonar: Department of Medical Neurobiology, Institute of Medical Research Israel–Canada (IMRIC), The Hebrew University–Hadassah Medical School
O. Marmor: Department of Medical Neurobiology, Institute of Medical Research Israel–Canada (IMRIC), The Hebrew University–Hadassah Medical School
R. Paz: Department of Neurobiology, Weizmann Institute of Science
Z. Israel: Department of Neurosurgery, Hadassah University Hospital
R. Eitan: Department of Medical Neurobiology, Institute of Medical Research Israel–Canada (IMRIC), The Hebrew University–Hadassah Medical School
H. Bergman: Department of Medical Neurobiology, Institute of Medical Research Israel–Canada (IMRIC), The Hebrew University–Hadassah Medical School

DOI: https://doi.org/10.1038/s41467-021-27375-5
Journal volume & issue: Vol. 12, no. 1
pp. 1 – 17

Abstract

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Dopamine tone modulation generates changes in beta oscillation physiology. Here the authors show beta frequency, and not power, coherence, phase-locking, or PAC is monotonically linked to dopamine tone and is likely the key property of pathological oscillations in cortical and basal ganglia networks.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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