PIEZO1 gain-of-function mutations delay reticulocyte maturation in hereditary xerocytosis

• Pedro L. Moura,
• Bethan R. Hawley,
• Johannes G.G. Dobbe,
• Geert J. Streekstra,
• Minke A.E. Rab,
• Paola Bianchi,
• Richard van Wijk,
• Ashley M. Toye,
• Timothy J. Satchwell

Affiliations

Pedro L. Moura

School of Biochemistry, University of Bristol, Bristol, UK;NIHR Blood and Transplant Research Unit in Red Cell Products, University of Bristol, Bristol, UK

Bethan R. Hawley

School of Biochemistry, University of Bristol, Bristol, UK;School of Physiology, Pharmacology and Neuroscience, University of Bristol,Britsol, UK

Johannes G.G. Dobbe

Amsterdam UMC, University of Amsterdam, Department of Biomedical Engineering and Physics, Amsterdam, the Netherlands

Geert J. Streekstra

Amsterdam UMC, University of Amsterdam, Department of Biomedical Engineering and Physics, Amsterdam, the Netherlands

Minke A.E. Rab

Department of Clinical Chemistry and Haematology, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands;Van Creveldkliniek, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands

Paola Bianchi

UOC Ematologia, UOS Fisiopatologia delle Anemie, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milano, Italy

Richard van Wijk

Department of Clinical Chemistry and Haematology, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands

Ashley M. Toye

School of Biochemistry, University of Bristol, Bristol, UK;NIHR Blood and Transplant Research Unit in Red Cell Products, University of Bristol, Bristol, UK;Bristol Institute for Transfusion Sciences, National Health Service Blood and Transplant (NHSBT), Bristol, UK

Timothy J. Satchwell

School of Biochemistry, University of Bristol, Bristol, UK;NIHR Blood and Transplant Research Unit in Red Cell Products, University of Bristol, Bristol, UK;Bristol Institute for Transfusion Sciences, National Health Service Blood and Transplant (NHSBT), Bristol, UK