Constrictive Pericarditis Caused by IgG4-Related Disease Requiring Pericardiectomy After Partial Response to Corticosteroids

Eugene Yuriditsky, MD; Aeshita Dwivedi, MD; Navneet Narula, MD; Leon Axel, MD; James M. Horowitz, MD; Mikhail Vaynblat, MD

JACC: Case Reports (Aug 2020)

Constrictive Pericarditis Caused by IgG4-Related Disease Requiring Pericardiectomy After Partial Response to Corticosteroids

Eugene Yuriditsky, MD,
Aeshita Dwivedi, MD,
Navneet Narula, MD,
Leon Axel, MD,
James M. Horowitz, MD,
Mikhail Vaynblat, MD

Affiliations

Eugene Yuriditsky, MD: Division of Cardiology, Department of Medicine, NYU Langone Medical Center, New York, New York; Address for correspondence: Dr. Eugene Yuriditsky, Leon H. Charney Division of Cardiology, Department of Medicine, NYU Langone Health, 530 First Avenue, Skirball 9R, New York, New York 10016.
Aeshita Dwivedi, MD: Division of Cardiology, Department of Medicine, NYU Langone Medical Center, New York, New York
Navneet Narula, MD: Department of Pathology and Laboratory Medicine, NYU Langone Medical Center, New York, New York
Leon Axel, MD: Department of Radiology, NYU Langone Medical Center, New York, New York
James M. Horowitz, MD: Division of Cardiology, Department of Medicine, NYU Langone Medical Center, New York, New York
Mikhail Vaynblat, MD: Department of Cardiothoracic Surgery, NYU Langone Medical Center, New York, New York

Journal volume & issue: Vol. 2, no. 10
pp. 1558 – 1563

Abstract

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Immunoglobulin G4–related disease is a systemic fibroinflammatory disease; pericardial involvement has occasionally been reported in publications. A 79-year-old man with biopsy-proven immunoglobulin G4–related disease with pleural involvement was admitted in acute heart failure, with imaging and hemodynamic studies consistent with constrictive pericarditis. He was treated with corticosteroids for 2 months with partial response manifest by decreases in pericardial thickening and immunoglobulin G4 levels. However, persistent constriction required pericardiectomy, leading to significant symptomatic improvement. (Level of Difficulty: Intermediate.)

Published in JACC: Case Reports

ISSN: 2666-0849 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine: Diseases of the circulatory (Cardiovascular) system
Website: https://www.journals.elsevier.com/jacc-case-reports

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Abstract

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