The Comparison of Clinical Features Between Patients with Positive and Negative Appendectomy

Abstract

INTRODUCTION: The objective of this study was to retrospectively compare clinical features and prognostic values between the patients who were referred to the general surgery clinic of our hospital with the presumed diagnosis of acute appendicitis and underwent positive or negative appendectomy. METHODS: Patients were divided into two groups as positive (n: 362) and negative appendectomy (n: 284) and the data obtained were compared between these two groups. Laboratory investigations were performed in all patients, and white blood cell, mean platelet volume (MPV), neutrophils count, neutrophils (%) (NEU%), C-reactive protein and total bilirubin (TBIL) values were studied. RESULTS: The mean CRP value was found as 57.68 in positive appendectomy (PA) group and 41.43 in negative appendectomy (NA) group, and the mean CRP value was statistically significantly higher in PA group, compared to NA group. The mean TBIL value was 0.97 mg/dl in PA group and 0.69 mg/dl in NA group, and the mean TBIL value was statistically significantly higher in PA group. The other parameters were similar between the groups. DISCUSSION AND CONCLUSION: According to the results of our study, CRP and TBIL values significantly differ between positive and negative appendectomy patients. Therefore, these values may be used as specific biomarkers in predicting positive acute appendicitis.

Keywords

• appendicitis
• appendectomy
• c-reactive protein
• bilirubin
• mean platelet volume