Eye and Brain (Sep 2022)
Value of Optic Nerve Sheath Diameter in Diagnosis and Follow Up of Patients with Disturbed Conscious Level
Abstract
Osama Mahmoud Momtaz,1 Omar M Said,2 Amany Mahmoud Mohamed,1 Tamer Sayed Abdel Mawla1 1Critical Care Department, Fayoum University, Fayoum, Egypt; 2Ophthalmology Department, Fayoum University, Fayoum, EgyptCorrespondence: Omar M Said, Ophthalmology Department, Fayoum University, Fayoum, Egypt, Email [email protected]: Ultrasonographic measurement of optic nerve sheath diameter is a simple, non-invasive, and reliable method of detecting elevated intracranial pressure (ICP) in critical patients. Optic nerve sheath communicates with the dura mater covering the brain and contains cerebrospinal fluid, allowing pressure transmission from the cranium. Therefore, changes in cerebrospinal fluid (CSF) pressure have been shown to produce changes in ONSD.Objective: This study aimed to assess the accuracy of optic nerve sheath diameter (ONSD) in diagnosis and follow-up patients with disturbed conscious levels compared with CT brain and fundus examination.Patients and Methods: One hundred forty-one participants were included in the study, classified into 76 cases admitted with disturbed conscious levels due to elevated ICP and 65 controls. All patients were subjected to CT brain and optic nerve US and fundus examination at the time of admission and follow-up after 48 h after proper management.Results: The current study showed that ONSD is significant in predicting elevated ICP at the cut-off point of average ONSD of 5.19 mm with 97% sensitivity and 98% specificity, and the area under the curve (AUC) was 0.996. The present study revealed a significant inverse correlation between ONSD and GCS in patients with increased ICP.Conclusion: Ultrasonic measurement of ONSD is a promising technique in diagnosing and following patients with disturbed conscious levels.Keywords: ultrasonographic, optic nerve sheath diameter, disturbed conscious level
