Детские инфекции (Москва) (Aug 2015)
FECAL CALPROTECTIN AS A MARKER OF INFLAMMATION IN THE COLON AT DIFFERENT VARIANTS OF CLOSTRIDIUM DIFFICILE-INFECTIONS COURSE IN CHILDREN
Abstract
The article discusses possible application of determination of the fecal calprotectin level in children with antibiotic-associated diarrhea caused by Clostridium difficile — infection to detect inflammation in various parts of the gastrointestinal tract. It is shown that calprotectin is an informative non-invasive method that can estimate the degree of inflammatory changes of the intestinal mucosa in patients with different clinical variants of Clostridium difficile — infection. The highest levels of fecal calprotectin are characteristic of hemorrhagic colitis caused by this microorganism.
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