Детские инфекции (Москва) (Aug 2015)

FECAL CALPROTECTIN AS A MARKER OF INFLAMMATION IN THE COLON AT DIFFERENT VARIANTS OF CLOSTRIDIUM DIFFICILE-INFECTIONS COURSE IN CHILDREN

  • L. N. Mazankova,
  • S. G. Gorbunov,
  • B. Yunes

DOI
https://doi.org/10.22627/2072-8107-2013-12-2-12-16
Journal volume & issue
Vol. 12, no. 2
pp. 12 – 16

Abstract

Read online

The article discusses possible application of determination of the fecal calprotectin level in children with antibiotic-associated diarrhea caused by Clostridium difficile — infection to detect inflammation in various parts of the gastrointestinal tract. It is shown that calprotectin is an informative non-invasive method that can estimate the degree of inflammatory changes of the intestinal mucosa in patients with different clinical variants of Clostridium difficile — infection. The highest levels of fecal calprotectin are characteristic of hemorrhagic colitis caused by this microorganism.

Keywords