Nature Communications (Jan 2021)

isoCirc catalogs full-length circular RNA isoforms in human transcriptomes

  • Ruijiao Xin,
  • Yan Gao,
  • Yuan Gao,
  • Robert Wang,
  • Kathryn E. Kadash-Edmondson,
  • Bo Liu,
  • Yadong Wang,
  • Lan Lin,
  • Yi Xing

DOI
https://doi.org/10.1038/s41467-020-20459-8
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 11

Abstract

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Circular RNAs have been identified using short-read RNA sequencing. Here, the authors report isoCirc, a long-read sequencing method to characterize full-length circRNA isoforms and generate a catalogue of full-length circRNA isoforms in 12 human tissues and one human cell line.