Emerging Infectious Diseases (Mar 2012)

Escherichia coli O104:H4 Infections and International Travel

  • David C. Alexander,
  • Weilong Hao,
  • Matthew W. Gilmour,
  • Sandra Zittermann,
  • Alicia Sarabia,
  • Roberto G. Melano,
  • Analyn Peralta,
  • Marina Lombos,
  • Keisha Warren,
  • Yuri Amatnieks,
  • Evangeline Virey,
  • Jennifer H. Ma,
  • Frances B. Jamieson,
  • Donald E. Low,
  • Vanessa Allen

DOI
https://doi.org/10.3201/eid1803.111281
Journal volume & issue
Vol. 18, no. 3
pp. 473 – 476

Abstract

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We analyzed travel-associated clinical isolates of Escherichia coli O104:H4, including 1 from the 2011 German outbreak and 1 from a patient who returned from the Philippines in 2010, by genome sequencing and optical mapping. Despite extensive genomic similarity between these strains, key differences included the distribution of toxin and antimicrobial drug–resistance determinants.

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