Lipid profile features of newborns from multiple pregnancy in the early neonatal period

Abstract

Purpose. The study aims at testing selected lipid metabolism indicators in newborns born to multiple pregnancies.Characteristics of children and research methods. The study included 99 newborns born to multiple pregnancies. The study set comprised 36 twins and 9 triples. Triglycerides and cholesterol were measured.Results. The content of blood triglycerides in children born of multiple pregnancies varies widely. The study found that 32% of newborns from twins and triplets have low perinatal TG production. For 12,5% of premature babies born 2nd or 3rd from twins or triplets, a critically low TG content (0,01–0,1 mmol/l) is characteristic. The TG content in the blood is not always the same in children at birth. Hypotriglyceridemia is associated with perinatal hypoxia, acute respiratory failure and the development of complications in the early neonatal period.Conclusion. Children born of a multiple pregnancy, at birth, tend to present with metabolic disorders of triglycerides and blood cholesterol of various degrees. The most characteristic pairs are: a very low TG content (less than 0,2 mmol/L) in one child and an average (0,21–05 mmol/L) in the other. All children from the triplet have different blood triglycerides, regardless of the order of birth. In the course of the early neonatal period the contents of triglycerides and blood cholesterol stabilize, but the triglyceride production rates are different. The most intensive rise is observed in twins with a low content of triglycerides at birth.

Keywords

• новорожденные
• многоплодие
• триглицериды
• холестерин