Hemodialysis acutely altered interferon-gamma release assay test result and immune cell profile

Denise Utami Putri; Chia-Ling Chen; Cheng-Hui Wang; Yuh-Mou Sue; Po-Chun Tseng; Chiou-Feng Lin; Ching-Wen Tsai; Yi-Jun Liu; Chih-Hsin Lee

Journal of Microbiology, Immunology and Infection (Apr 2022)

Hemodialysis acutely altered interferon-gamma release assay test result and immune cell profile

Denise Utami Putri,
Chia-Ling Chen,
Cheng-Hui Wang,
Yuh-Mou Sue,
Po-Chun Tseng,
Chiou-Feng Lin,
Ching-Wen Tsai,
Yi-Jun Liu,
Chih-Hsin Lee

Affiliations

Denise Utami Putri: Pulmonary Research Center, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan
Chia-Ling Chen: Pulmonary Research Center, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan; School of Respiratory Therapy, College of Medicine, Taipei Medical University, Taipei, Taiwan
Cheng-Hui Wang: Pulmonary Research Center, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan; Department of Laboratory Medicine, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan; School of Medical Laboratory Science and Biotechnology, College of Medical Science and Technology, Taipei Medical University, Taipei, Taiwan
Yuh-Mou Sue: Division of Nephrology, Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan; Division of Nephrology, Department of Internal Medicine, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan
Po-Chun Tseng: Department of Microbiology and Immunology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan; Immune Monitoring Core, Office of Research and Development, Taipei Medical University, Taipei, Taiwan
Chiou-Feng Lin: Department of Microbiology and Immunology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan; Immune Monitoring Core, Office of Research and Development, Taipei Medical University, Taipei, Taiwan; Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei, Taiwan
Ching-Wen Tsai: Research Center of Biostatistics, College of Management, Taipei Medical University, Taipei, Taiwan
Yi-Jun Liu: Pulmonary Research Center, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan
Chih-Hsin Lee: Pulmonary Research Center, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan; Department of Internal Medicine, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan; Division of Pulmonary Medicine, Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan; Corresponding author. Tuberculosis Center and Pulmonary Research Center, Wan Fang Hospital, Taipei Medical University, 111, Sec. 3, Xinglong Rd. Wenshan Dist., Taipei, 116, Taiwan. Fax: +886 2930 2448.

Journal volume & issue: Vol. 55, no. 2
pp. 332 – 335

Abstract

Read online

Patients receiving hemodialysis (HD) are at risk of TB development. IGRA-positive patients showed significant decrease in quantitative IGRA result with alterations in CD3+CD4+CD45RO+, NK cell, and monocyte subsets immediately upon HD procedure. Our result suggested that the timing of IGRA testing is crucial in end-stage renal disease population.

Published in Journal of Microbiology, Immunology and Infection

ISSN: 1684-1182 (Print)
Publisher: Elsevier
Country of publisher: Hong Kong
LCC subjects: Science: Microbiology
Website: https://www.sciencedirect.com/journal/journal-of-microbiology-immunology-and-infection

About the journal

Abstract

Keywords