Natural Products and Bioprospecting (May 2018)

Three New Heptelidic Acid Derivatives from the Culture of Mushroom Lentinellus ursinus

  • Li Liu,
  • Jun-Jie Han,
  • Tian-Shun Xu,
  • Rui-Xing Liu,
  • Li Bao,
  • Hong-Wei Liu

DOI
https://doi.org/10.1007/s13659-018-0168-8
Journal volume & issue
Vol. 8, no. 5
pp. 355 – 360

Abstract

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Abstract Three new heptelidic acid derivatives (1–3) including two new dimeric esters and two known heptelidic acid analogues (4 and 5) were isolated from the solid culture of mushroom Lentinellus ursinus. The structures of new compounds were confirmed by the analysis of NMR and HRESIMS spectroscopic data. The biosynthetic origin of compounds 1–5 was postulated. Compounds 1–5 exhibited no antibacterial activity against Staphylococcus aureus and Escherichia coli at the dose of 100 μM. Graphical Abstract

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