Research progress of single nucleotide polymorphism and development of high myopia

Shan-Shan Wu; Da-Dong Guo; De-Zheng Liu; Ling-Ling Yin; Wen-Jun Jiang; Hong-Sheng Bi

doi:10.3980/j.issn.1672-5123.2019.9.11

Guoji Yanke Zazhi (Sep 2019)

Research progress of single nucleotide polymorphism and development of high myopia

Shan-Shan Wu,
Da-Dong Guo,
De-Zheng Liu,
Ling-Ling Yin,
Wen-Jun Jiang,
Hong-Sheng Bi

Affiliations

Shan-Shan Wu: Shandong University of Traditional Chinese Medicine, Jinan 250014, Shandong Province, China; Shandong Provincial Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Therapy of Ocular Diseases, Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention an Therapy of Ocular Disease in University of Shandong, Eye Institute of Shandong University of Traditional Chinese Medicine, Jinan 250002, Shandong Province, China
Da-Dong Guo: Shandong Provincial Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Therapy of Ocular Diseases, Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention an Therapy of Ocular Disease in University of Shandong, Eye Institute of Shandong University of Traditional Chinese Medicine, Jinan 250002, Shandong Province, China
De-Zheng Liu: Shandong University of Traditional Chinese Medicine, Jinan 250014, Shandong Province, China; Shandong Provincial Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Therapy of Ocular Diseases, Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention an Therapy of Ocular Disease in University of Shandong, Eye Institute of Shandong University of Traditional Chinese Medicine, Jinan 250002, Shandong Province, China
Ling-Ling Yin: People's Hospital of Dongying City, Dongying 257091, Shandong Province, China
Wen-Jun Jiang: Shandong Provincial Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Therapy of Ocular Diseases, Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention an Therapy of Ocular Disease in University of Shandong, Eye Institute of Shandong University of Traditional Chinese Medicine, Jinan 250002, Shandong Province, China
Hong-Sheng Bi: Shandong Provincial Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Therapy of Ocular Diseases, Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention an Therapy of Ocular Disease in University of Shandong, Eye Institute of Shandong University of Traditional Chinese Medicine, Jinan 250002, Shandong Province, China; Affiliated Eye Hospital of Shandong University of Traditional Chinese Medicine, Jinan 250002, Shandong Province, China

DOI: https://doi.org/10.3980/j.issn.1672-5123.2019.9.11
Journal volume & issue: Vol. 19, no. 9
pp. 1495 – 1498

Abstract

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At present, myopia has become a public health disease worldwide, and its occurrence is mostly caused by genetic and environmental factors. Single nucleotide polymorphisms(SNPs)are the changes in single base at the genomic level caused by DNA sequence polymorphisms. In recent years, it is reported that the change of SNPs in myopic related gene loci is closely related to the occurrence and development of myopia. The present paper reviewed the current status of the association between SNPs of myopia-related genes and the development of myopia, providing a new insight into the future research of pathogenesis of myopia.

Published in Guoji Yanke Zazhi

ISSN: 1672-5123 (Print)
Publisher: Press of International Journal of Ophthalmology (IJO PRESS)
Country of publisher: China
LCC subjects: Medicine: Ophthalmology
Website: http://ies.ijo.cn/

About the journal

Abstract

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