Nature Communications (Apr 2020)

Structural basis of astrocytic Ca2+ signals at tripartite synapses

  • Misa Arizono,
  • V. V. G. Krishna Inavalli,
  • Aude Panatier,
  • Thomas Pfeiffer,
  • Julie Angibaud,
  • Florian Levet,
  • Mirelle J. T. Ter Veer,
  • Jillian Stobart,
  • Luigi Bellocchio,
  • Katsuhiko Mikoshiba,
  • Giovanni Marsicano,
  • Bruno Weber,
  • Stéphane H. R. Oliet,
  • U. Valentin Nägerl

DOI
https://doi.org/10.1038/s41467-020-15648-4
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 15

Abstract

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Astrocytic Ca2+ signals can be fast and local, supporting the idea that astrocytes have the ability to regulate single synapses. Here, the authors report the organization of astrocytes at nanoscale level and identify nodes as a functional astrocytic component of tripartite synapses.