Acta Crystallographica Section E (Apr 2010)

(6R)-2-tert-Butyl-6-[(4R,5S)-3-isopropyl-4-methyl-5-phenyloxazolidin-2-yl]phenol

  • Takaoki Koyanagi,
  • Kate L. Edler,
  • Raleigh W. Parrott II,
  • Shawn R. Hitchcock,
  • Gregory M. Ferrence

DOI
https://doi.org/10.1107/S1600536810009591
Journal volume & issue
Vol. 66, no. 4
pp. o898 – o899

Abstract

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In the title compound, C23H31NO2, the lone pair on the nitrogen atom is oriented to facilitate intramolecular hydrogen bonding with the hydroxy group residing on the phenyl substituent. The five-membered ring adopts an envelope confornmation with the O atom at the flap. The absolute stereochemistry was verified by measurement of optical activity using a digital polarimeter.