Translational Neuroscience (Feb 2020)

Advances in transcription factors related to neuroglial cell reprogramming

  • Liu Kuangpin,
  • Ma Wei,
  • Li Chunyan,
  • Li Junjun,
  • Zhang Xingkui,
  • Liu Jie,
  • Liu Wei,
  • Wu Zheng,
  • Zang Chenghao,
  • Liang Yu,
  • Guo Jianhui,
  • Li Liyan

DOI
https://doi.org/10.1515/tnsci-2020-0004
Journal volume & issue
Vol. 11, no. 1
pp. 17 – 27

Abstract

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Neuroglial cells have a high level of plasticity, and many types of these cells are present in the nervous system. Neuroglial cells provide diverse therapeutic targets for neurological diseases and injury repair. Cell reprogramming technology provides an efficient pathway for cell transformation during neural regeneration, while transcription factor-mediated reprogramming can facilitate the understanding of how neuroglial cells mature into functional neurons and promote neurological function recovery.

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