Nature Communications (Dec 2020)

A conserved regulator controls asexual sporulation in the fungal pathogen Candida albicans

  • Arturo Hernández-Cervantes,
  • Sadri Znaidi,
  • Lasse van Wijlick,
  • Iryna Denega,
  • Virginia Basso,
  • Jeanne Ropars,
  • Natacha Sertour,
  • Derek Sullivan,
  • Gary Moran,
  • Louise Basmaciyan,
  • Fabienne Bon,
  • Frédéric Dalle,
  • Marie-Elisabeth Bougnoux,
  • Teun Boekhout,
  • Ying Yang,
  • Zongwei Li,
  • Sophie Bachellier-Bassi,
  • Christophe d’Enfert

DOI
https://doi.org/10.1038/s41467-020-20010-9
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 16

Abstract

Read online

Transcription factor Rme1 regulates meiosis and pseudohyphal growth in baker’s yeast, but its role in the meiosis-defective pathogen Candida albicans is unclear. Here, Hernández-Cervantes et al. show that Rme1 activates the expression of genes required for formation of asexual spores in Candida species.