Production of Itaconic Acid Through Microbiological Fermentation of Inexpensive Materials

Jing Yang; Hao Xu; Jianchun Jiang; Ning Zhang; Jingcong Xie; Min Wei; Jian Zhao

Journal of Bioresources and Bioproducts (Aug 2019)

Production of Itaconic Acid Through Microbiological Fermentation of Inexpensive Materials

Jing Yang,
Hao Xu,
Jianchun Jiang,
Ning Zhang,
Jingcong Xie,
Min Wei,
Jian Zhao

Affiliations

Jing Yang: Institute of Chemical Industry of Forest Products, Chinese Academy of Forestry; National Engineering Laboratory for Biomass Chemical Utilization; Key and Open Laboratory of Forest Chemical Engineering, State Forestry Administration; Key Laboratory of Biomass Energy and Material, Jiangsu Province; Nanjing, 210042, China; Co-Innovation Center of Efficient Processing and Utilization of Forest Resources, Nanjing Forestry University, Nanjing 210037, China
Hao Xu: Institute of Chemical Industry of Forest Products, Chinese Academy of Forestry; National Engineering Laboratory for Biomass Chemical Utilization; Key and Open Laboratory of Forest Chemical Engineering, State Forestry Administration; Key Laboratory of Biomass Energy and Material, Jiangsu Province; Nanjing, 210042, China; Co-Innovation Center of Efficient Processing and Utilization of Forest Resources, Nanjing Forestry University, Nanjing 210037, China
Jianchun Jiang: Institute of Chemical Industry of Forest Products, Chinese Academy of Forestry; National Engineering Laboratory for Biomass Chemical Utilization; Key and Open Laboratory of Forest Chemical Engineering, State Forestry Administration; Key Laboratory of Biomass Energy and Material, Jiangsu Province; Nanjing, 210042, China; Co-Innovation Center of Efficient Processing and Utilization of Forest Resources, Nanjing Forestry University, Nanjing 210037, China
Ning Zhang: Institute of Chemical Industry of Forest Products, Chinese Academy of Forestry; National Engineering Laboratory for Biomass Chemical Utilization; Key and Open Laboratory of Forest Chemical Engineering, State Forestry Administration; Key Laboratory of Biomass Energy and Material, Jiangsu Province; Nanjing, 210042, China; Co-Innovation Center of Efficient Processing and Utilization of Forest Resources, Nanjing Forestry University, Nanjing 210037, China
Jingcong Xie: Institute of Chemical Industry of Forest Products, Chinese Academy of Forestry; National Engineering Laboratory for Biomass Chemical Utilization; Key and Open Laboratory of Forest Chemical Engineering, State Forestry Administration; Key Laboratory of Biomass Energy and Material, Jiangsu Province; Nanjing, 210042, China; Co-Innovation Center of Efficient Processing and Utilization of Forest Resources, Nanjing Forestry University, Nanjing 210037, China
Min Wei: Institute of Chemical Industry of Forest Products, Chinese Academy of Forestry; National Engineering Laboratory for Biomass Chemical Utilization; Key and Open Laboratory of Forest Chemical Engineering, State Forestry Administration; Key Laboratory of Biomass Energy and Material, Jiangsu Province; Nanjing, 210042, China; Co-Innovation Center of Efficient Processing and Utilization of Forest Resources, Nanjing Forestry University, Nanjing 210037, China
Jian Zhao: Institute of Chemical Industry of Forest Products, Chinese Academy of Forestry; National Engineering Laboratory for Biomass Chemical Utilization; Key and Open Laboratory of Forest Chemical Engineering, State Forestry Administration; Key Laboratory of Biomass Energy and Material, Jiangsu Province; Nanjing, 210042, China; Co-Innovation Center of Efficient Processing and Utilization of Forest Resources, Nanjing Forestry University, Nanjing 210037, China

Journal volume & issue: Vol. 4, no. 3
pp. 135 – 142

Abstract

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Itaconic acid (IA) is a precursor of various chemicals, which has been on the US Department of Energy’s list of the top 12 platform chemicals that can potentially be produced from biomass. The IA is mainly produced through a bio-fermentation method with sugar as raw material. However, the high cost and low yield restrict the industrial application of the IA. This review summarized research advances in the IA production from alternative substrates. In particular, the types of substrates as well as existing problems in the IA fermentation, strain breeding, and process regulation were discussed. And it is pointed that decreasing the price of the IA with alternative substrates and increasing the titer through genetic engineering should be further focused on to support the industrialization of the IA.

Published in Journal of Bioresources and Bioproducts

ISSN: 2369-9698 (Online)
Publisher: KeAi Communications Co., Ltd.
Country of publisher: China
LCC subjects: Science: Chemistry: Organic chemistry: Biochemistry
Website: https://www.keaipublishing.com/en/journals/journal-of-bioresources-and-bioproducts/

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