Effect of folic acid, vitamin B12, and B6 supplementation on the risk of cardiovascular and cerebrovascular diseases: An updated meta-analysis of randomized controlled trials
Ye Man,
Chen Xiaohong,
Mao Sufang,
Zhou Jing,
Liu Minfen,
Wu Yu
Affiliations
Ye Man
Department of Neurology, The People’s Hospital of Lishui, No. 15, Dazhong Road, Liandu District, Lishui, Zhejiang Province 323000, China
Chen Xiaohong
Department of Neurology, The People’s Hospital of Lishui, No. 15, Dazhong Road, Liandu District, Lishui, Zhejiang Province 323000, China
Mao Sufang
Department of Neurology, The People’s Hospital of Lishui, No. 15, Dazhong Road, Liandu District, Lishui, Zhejiang Province 323000, China
Zhou Jing
Department of Neurology, The People’s Hospital of Lishui, No. 15, Dazhong Road, Liandu District, Lishui, Zhejiang Province 323000, China
Liu Minfen
Department of Neurology, The People’s Hospital of Lishui, No. 15, Dazhong Road, Liandu District, Lishui, Zhejiang Province 323000, China
Wu Yu
Department of Neurology, The People’s Hospital of Lishui, No. 15, Dazhong Road, Liandu District, Lishui, Zhejiang Province 323000, China
Numerous studies indicated that B vitamin supplementation can reduce cardiovascular risk; nonetheless, available proof reported from individual studies have not been consistent, so we performed an updated meta-analysis of randomized controlled trials (RCTs) to evaluate the relationship between B vitamin supplementation and cardiovascular outcomes.
