Clinical effectiveness of dynamical electroneurostimulation in combined therapy for hypertension

Abstract

To study possibilities of improving of blood pressure (BP) control using the DENS device in patients with arterial hypertension stages I-II. Placebo-controlled study of antihypertensive effect of diaDENS-cardio in 60 patients with arterial hypertension taking regular antihypertensive therapy. Measurements of BP were performed by self BP control and 24 hours monitoring of BP. According to results of both self BP control (123,4 ± 5,4 vs 144,9 ± 7,4 мм рт.ст., p < 0,05) and 24 hours monitoring of BP (125,8 ± 4,9 vs 147,1 ± 11,7 mm Hg, p < 0,05) decrease in systolic BP in groups using device diaDENS-cardio was observed. Decrease in BP in patients using device diaDENS-cardio resulted in reduced doses of ACE (enalapril 7,8 ± 5,7 vs 19,7 ± 10,2 mg/days, p < 0,01) and beta-blockers doses (metoprolol 40,8 ± 19,1 vs 75,8 ± 35,6 mg/days, p < 0,05) for optimum BP control. Using of active device diaDENS-cardio in patients with arterial hypertension helps to attain targeted BP values with lower drug doses.

Keywords

• антигипертензивная эффективность ДиаДЭНС-кардио
• акупунктура точки Нэй-Гуань
• вариабельность АД
• нагрузка давлением
• лекарственная нагрузка