Frontiers in Immunology (Sep 2023)

Case Report: High-dose steroid and IVIG successful treatment in a case of COVID-19-associated autoimmune encephalitis: a literature review

  • Chi-Hung Liu,
  • Li-Chung Chiu,
  • Chih-Chun Lee,
  • Tien-Ming Chan

DOI
https://doi.org/10.3389/fimmu.2023.1240089
Journal volume & issue
Vol. 14

Abstract

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Autoimmune encephalitis is a rare but critical complication of COVID-19. The management of COVID-19-associated autoimmune encephalitis includes the use of steroids, intravenous immunoglobulin (IVIG), plasmapheresis, and monoclonal antibody therapy. This study presented a patient with critical COVID-19 autoimmune encephalitis who rapidly recovered after the initiation of corticosteroids and IVIG therapy. This study reviewed the current literature on the pathophysiological mechanisms, diagnosis, and management of COVID-19-associated autoimmune encephalitis.

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