Open Medicine (Jan 2016)

Descending necrotizing mediastinitis in the elderly patients

  • Mazzella Antonio,
  • Santagata Mario,
  • Cecere Atirge,
  • La Mart Ettore,
  • Fiorelli Alfonso,
  • Tartaro Gianpaolo,
  • Tafuri Domenico,
  • Testa Domenico,
  • Grella Edoardo,
  • Perrotta Fabio,
  • Bianco Andrea,
  • Mazzarella Gennaro,
  • Santini Mario

DOI
https://doi.org/10.1515/med-2016-0080
Journal volume & issue
Vol. 11, no. 1
pp. 449 – 460

Abstract

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Descending Necrotizing Mediastinitis (DNM) is a polymicrobic, dangerous and often fatal process, arising from head or neck infections and spreading along the deep fascial cervical planes, descending into the mediastinum. It can rapidly progress to sepsis and can frequently lead to death. It has a high mortality rate, up to 40% in the different series, as described in the literature. Surgical and therapeutic management has been discussed for long time especially in an elderly patient population. The literature has been reviewed in order to evaluate different pathogenesis and evolution and to recognise a correct therapeutic management.

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