Diabetology & Metabolic Syndrome (Oct 2009)

Estimating cardiovascular risk in patients with type 2 diabetes: a national multicenter study in Brazil

  • Gomes Marilia B,
  • Giannella-Neto Daniel,
  • Faria Manuel,
  • Tambascia Marcos,
  • Fonseca Reine M,
  • Rea Rosangela,
  • Macedo Geisa,
  • Modesto-Filho João,
  • Schmid Helena,
  • Bittencourt Alcina V,
  • Cavalcanti Saulo,
  • Rassi Nelson,
  • Pedrosa Hermelinda,
  • Dib Sergio A

DOI
https://doi.org/10.1186/1758-5996-1-22
Journal volume & issue
Vol. 1, no. 1
p. 22

Abstract

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Abstract According to Brazilian National Data Survey diabetes is the fifth cause for hospitalization and is one of the ten major causes of mortality in this country. Aims to stratify the estimated cardiovascular risk (eCVR) in a population of type 2 diabetics (T2DM) according to the Framingham prediction equations as well as to determine the association between eCVR with metabolic and clinical control of the disease. Methods From 2000 to 2001 a cross-sectional multicenter study was conducted in 13 public out-patients diabetes/endocrinology clinics from 8 Brazilian cities. The 10-year risk of developing coronary heart disease (CHD) was estimated by the prediction equations described by Wilson et al (Circulation 1998). LDL equations were preferably used; when patients missed LDL data we used total cholesterol equations instead. Results Data from 1382 patients (59.0% female) were analyzed. Median and inter-quartile range (IQ) of age and duration of diabetes were 57.4 (51-65) and 8.8 (3-13) years, respectively without differences according to the gender. Forty-two percent of these patients were overweight and 35.4% were obese (the prevalence of higher BMI and obesity in this T2DM group was significantly higher in women than in men; p 20%) in 738 (53.4%), intermediate in 202 (14.6%) and low in 442 (32%) patients. Men [25.1(15.4-37.3)] showed a higher eCVR than women [18.8 (12.4-27.9) p