The spectrum of ABO and rhesus blood group systems in a blood center in Southern Karnataka

Abstract

Introduction: Hereditary characteristics, such as ABO and Rhesus (Rh) blood group antigens, are helpful for population genetic studies, for settling medicolegal disputes, and most vitally immunologic safety of blood during transfusion. Having firm knowledge of blood grouping is essential for managing the collection of blood banks. It can lower the likelihood of morbidity and mortality brought on by lack of blood in specific areas. The objective of our study was to screen and determine the frequencies of the occurrence of ABO and Rh blood groups among residents from both the urban and rural populations of the South Karnataka region. Materials and Methods: This was a retrospective study. The study was conducted in a blood center and included all the donors from January 17 to December 22. Hemoglobin estimation was estimated by copper sulfate method and ERMA INC-PCE-210 3-Part analyzer. After blood bank validation, Tulip Diagnostics Limited standard anti-sera of anti-A, anti-B, and anti-D were used to conduct antigen–antibody slide agglutination test to determine the ABO grouping and Rh typing following blood donation. Simple percentages were used to report data on the ABO and Rh blood group distribution patterns. Results: Out of 19497 donors, predominant age group was 25–29 years (29.46%). The male:female ratio was 108:1. Voluntary donors (91.03%) were more than replacement donors, with predominant donors being Rh positive. Maximum donors had the blood group O (42.5%), followed by B > A > AB. There were also four Bombay blood group donors in our study. Conclusion: Good knowledge and understanding of blood grouping have an imperative involvement in the management of blood bank inventory. It can help to minimize the morbidity and mortality rate due to lack of blood in a particular geographical area.

Keywords

• abo
• blood groups
• donors
• rhesus