An atlas of protein turnover rates in mouse tissues

Zach Rolfs; Brian L. Frey; Xudong Shi; Yoshitaka Kawai; Lloyd M. Smith; Nathan V. Welham

doi:10.1038/s41467-021-26842-3

Nature Communications (Nov 2021)

An atlas of protein turnover rates in mouse tissues

Zach Rolfs,
Brian L. Frey,
Xudong Shi,
Yoshitaka Kawai,
Lloyd M. Smith,
Nathan V. Welham

Affiliations

Zach Rolfs: Department of Chemistry, University of Wisconsin-Madison
Brian L. Frey: Department of Chemistry, University of Wisconsin-Madison
Xudong Shi: Division of Otolaryngology–Head and Neck Surgery, Department of Surgery, University of Wisconsin School of Medicine and Public Health
Yoshitaka Kawai: Division of Otolaryngology–Head and Neck Surgery, Department of Surgery, University of Wisconsin School of Medicine and Public Health
Lloyd M. Smith: Department of Chemistry, University of Wisconsin-Madison
Nathan V. Welham: Division of Otolaryngology–Head and Neck Surgery, Department of Surgery, University of Wisconsin School of Medicine and Public Health

DOI: https://doi.org/10.1038/s41467-021-26842-3
Journal volume & issue: Vol. 12, no. 1
pp. 1 – 9

Abstract

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Protein turnover underpins biology but is challenging to measure in vivo across the entire proteome. Here, the authors provide a comprehensive resource of protein turnover in mouse tissues and develop a visualization platform to analyze these data.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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