Cellular sensitivity of white blood cell in vitro to interferon-α2 in the dynamics of ebv-infections in children

Abstract

In this study, the cellular sensitivity of white blood cells in vitro to interferon-α2 in children with EBV-infection in the acute period of the disease in terms of the 1, 6, 12 months after a previous infection. Found that children in the dynamics of the EBV-infection, preservation of cell sensitivity at the same level at 1 month after the disease is seen in 40,5% children, 6 months – 27,8% patients. Lack of cell sensitivity to interferon-α2 blood leukocytes in 12 months after undergoing a EBV-infection observed in 88,9% of children. During repeated courses interferon-therapy to study cellular sensitivity of blood leukocytes for individual selection of the drug.

Keywords

• ebv-infection
• cellular sensitivity
• interferon-α2
• white blood cells
• children