Журнал инфектологии (Sep 2014)

Cellular sensitivity of white blood cell in vitro to interferon-α2 in the dynamics of ebv-infections in children

  • M. B. Dryganova,
  • G. P. Martynova,
  • L. M. Kurtasova,
  • S. V. Evreimova

DOI
https://doi.org/10.22625/2072-6732-2013-5-2-32-36
Journal volume & issue
Vol. 5, no. 2
pp. 32 – 36

Abstract

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In this study, the cellular sensitivity of white blood cells in vitro to interferon-α2 in children with EBV-infection in the acute period of the disease in terms of the 1, 6, 12 months after a previous infection. Found that children in the dynamics of the EBV-infection, preservation of cell sensitivity at the same level at 1 month after the disease is seen in 40,5% children, 6 months – 27,8% patients. Lack of cell sensitivity to interferon-α2 blood leukocytes in 12 months after undergoing a EBV-infection observed in 88,9% of children. During repeated courses interferon-therapy to study cellular sensitivity of blood leukocytes for individual selection of the drug.

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