Advanced Imaging Techniques for Assessing Fat, Iron, and Fibrosis in Chronic Liver Disease
Sabarish Narayanasamy,
Manuela Franca,
Ilkay S. Idilman,
Meng Yin,
Sudhakar K. Venkatesh
Affiliations
Sabarish Narayanasamy
Department of Radiology, Mayo Clinic, Rochester, MN, USA
Manuela Franca
Department of Radiology, Santo António University Hospital Centre, School of Medicine and Biomedical Sciences (ICBAS), University of Porto, Porto, Portugal
Ilkay S. Idilman
Department of Radiology, Liver Imaging Team, Hacettepe University, Ankara, Turkiye
Meng Yin
Department of Radiology, Mayo Clinic, Rochester, MN, USA
Sudhakar K. Venkatesh
Department of Radiology, Mayo Clinic, Rochester, MN, USA
Imaging plays a critical role in the management of chronic liver disease (CLD) because it is a safe and painless method to assess liver health. The widely used imaging techniques include ultrasound, computed tomography and magnetic resonance imaging. These techniques allow the measurement of fat deposition, iron content, and fibrosis, replacing invasive liver biopsies in many cases. Early detection and treatment of fibrosis are crucial, as the disease can be reversed in its early stages. Imaging also aids in guiding treatment decisions and monitoring disease progression. In this review, we describe the most common imaging manifestations of liver disease and the current state-of-the-art imaging techniques for the evaluation of liver fat, iron, and fibrosis.