Beilstein Journal of Organic Chemistry (Apr 2012)
2-Allylphenyl glycosides as complementary building blocks for oligosaccharide and glycoconjugate synthesis
Abstract
The O-allylphenyl (AP) anomeric moiety was investigated as a new leaving group that can be activated for chemical glycosylation under a variety of conditions, through both direct and remote pathways. Differentiation between the two activation pathways was achieved in a mechanistic study. The orthogonal-type activation of the AP moiety along with common thioglycosides allows for the execution of efficient oligosaccharide assembly.
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