Genel Tıp Dergisi (Oct 2023)

Different Approach on our Cells and the Use of CRISPR/Cas 9 Technology: Super Gene'ethic

  • Ayşenur Taşkaya,
  • Ayşe Nur Akmeşe,
  • Himmet Akkaya,
  • Ece Demirel,
  • Sümeyra Demir,
  • Emine Kav,
  • Şengül Koçer,
  • Elif Senanur Yüksel,
  • Pelin Bacak,
  • Serap Karakaya,
  • Mohammed Saleh Ameen Al Qadri,
  • Hale Köksoy

DOI
https://doi.org/10.54005/geneltip.1332161
Journal volume & issue
Vol. 33, no. 5
pp. 594 – 598

Abstract

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Aims: CRISPR/Cas9, a revolutionary genome editing tool derived from a bacterial system, has transformed molecular biology research, enabling precise and versatile modifications to the genome. This study surveyed 300 participants, including instructors, second-year medical students, and patient relatives from Selcuk University Faculty of Medicine, to assess their knowledge, attitudes, and ethical perspectives on gene editing. Methods: A comprehensive survey was conducted, and the participants' demographics were correlated with their responses. Statistical analysis was performed using SPSS 22.0. Results: The survey revealed significant differences (p<0.05) in attitudes based on gender, age, and participation groups. The age group of 18-29 exhibited the highest participation rate (57.3%), while the age group of 60-65 had the lowest (1%). Approximately 50.3% of participants reported no prior knowledge of CRISPR/Cas9, and 64.3% were university graduates. Obtaining approval from ethics committees was considered crucial by 151 respondents for commencing CRISPR/Cas9 research. Interestingly, 63.3% showed eagerness for genetically modified plants and animals, while only 9% expressed interest in studies related to eternal youth. Additionally, 88% found gene editing studies conflicting with their beliefs. Conclusions: CRISPR/Cas9 holds great promise for biomedicine and healthcare but necessitates enhanced public awareness and informed decision-making. The study highlights the importance of promoting informed discussions on the ethical implications of CRISPR/Cas9 to address the concerns and perceptions of various demographics. These valuable insights contribute to the ongoing discourse on the impact of CRISPR/Cas9 on society.

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