Infantile BCG osteomyelitis ultimately diagnosed as a result of trauma

Katsuhiko Tabata, MD; Osamu Miyazaki, MD; Ayako Imai, MD; Reiko Okamoto, MD; Mikiko Miyasaka, MD; Yoshiyuki Tsutsumi, MD; Yoko Anami, MD; Atsuhito Seki, MD; Tatsuki Ikuse, MD, PhD; Toshinao Kawai, MD, PhD; Takashi Ishikawa, MD, PhD; Chizuko Haga, MD; Takako Yoshioka, MD; Shunsuke Nosaka, MD

Radiology Case Reports (Mar 2025)

Infantile BCG osteomyelitis ultimately diagnosed as a result of trauma

Katsuhiko Tabata, MD,
Osamu Miyazaki, MD,
Ayako Imai, MD,
Reiko Okamoto, MD,
Mikiko Miyasaka, MD,
Yoshiyuki Tsutsumi, MD,
Yoko Anami, MD,
Atsuhito Seki, MD,
Tatsuki Ikuse, MD, PhD,
Toshinao Kawai, MD, PhD,
Takashi Ishikawa, MD, PhD,
Chizuko Haga, MD,
Takako Yoshioka, MD,
Shunsuke Nosaka, MD

Affiliations

Katsuhiko Tabata, MD: Department of Radiology, National Center for Child Health and Development, Setagaya-ku, Tokyo, 157-8535, Japan; Department of Pediatrics, Saitama Medical University, Japan; Corresponding author.
Osamu Miyazaki, MD: Department of Radiology, National Center for Child Health and Development, Setagaya-ku, Tokyo, 157-8535, Japan
Ayako Imai, MD: Department of Radiology, National Center for Child Health and Development, Setagaya-ku, Tokyo, 157-8535, Japan
Reiko Okamoto, MD: Department of Radiology, National Center for Child Health and Development, Setagaya-ku, Tokyo, 157-8535, Japan
Mikiko Miyasaka, MD: Department of Radiology, National Center for Child Health and Development, Setagaya-ku, Tokyo, 157-8535, Japan
Yoshiyuki Tsutsumi, MD: Department of Radiology, National Center for Child Health and Development, Setagaya-ku, Tokyo, 157-8535, Japan
Yoko Anami, MD: Division of Orthopedic Surgery, National Center for Child Health and Development
Atsuhito Seki, MD: Division of Orthopedic Surgery, National Center for Child Health and Development
Tatsuki Ikuse, MD, PhD: Division of Infectious Diseases, National Center for Child Health and Development
Toshinao Kawai, MD, PhD: Division of Immunology, National Center for Child Health and Development
Takashi Ishikawa, MD, PhD: Division of Immunology, National Center for Child Health and Development
Chizuko Haga, MD: Department of Pathology, National Center for Child Health and Development
Takako Yoshioka, MD: Department of Pathology, National Center for Child Health and Development
Shunsuke Nosaka, MD: Department of Radiology, National Center for Child Health and Development, Setagaya-ku, Tokyo, 157-8535, Japan

Journal volume & issue: Vol. 20, no. 3
pp. 1784 – 1789

Abstract

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The BCG vaccine is effective in preventing severe tuberculosis infections in infants and young children, and it is commonly administered in Japan to those aged between 5 to 8 months. Although the incidence of adverse reactions is low, disseminated lymphadenitis and osteomyelitis have been reported as potential side effects. We encountered a case of BCG osteomyelitis with typical imaging findings. Provided the clinical presentation and imaging features are recognized, it is possible to diagnose BCG osteomyelitis definitively and exclude a number of possible differential diagnoses.

Published in Radiology Case Reports

ISSN: 1930-0433 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Medicine: Medicine (General): Medical physics. Medical radiology. Nuclear medicine
Website: https://www.sciencedirect.com/journal/radiology-case-reports

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